An Evaluation Of The Retention Property Between Cream Type And Strip Type Denture Adhesive With And Without Salivary Substitutes: An In Vitro Study

Background:Patients with xerostomia complain of not only dryness of mouth but also discomfort during routine normal oral functions like speaking and swallowing. These complainis worse in individuals wearing removable intraoral dental prosthesis. In such situations, when salivary flow decreases, denture adhesives and salivary substitutes are recommended; which aid in denture retention and improve patient comfort.Material & Method:A total 150 samples were prepared using heat-cure acrylic resin of 30mm×30mm×5mm. All samples were equally divided in A,B,C,D,E groups,wherein Group A was control group with salivary substitutes.Group B was denture adhesive cream without salivary substitutes.Group C was denture adhesive cream with salivary substitutes.Group D was denture adhesive strips without salivary substitutes.Group E was denture adhesive strips with salivary substitutes.The retentive force was measured for all samples usinguniversal testing machine.Results:Data was collected and statistical analysis was done by one-way ANOVA test followed by post hoc test. The significant difference was found between the retentive forces of cream type and strip type denture adhesives withor without salivary substitutes.Conclusion:From this study, it is concluded that denture adhesive will definitely increases the denture retention. The cream type denture adhesive with salivary substitutes has the most retention than among all groups.

Determining Efficacy and Minimum Inhibitory Concentrations of a Denture Adhesive Containing Particles and Nanoparticles of Zirconium against Candida albicans.

Candidiasis as a common complication in patients who wear dentures. Zirconia particles and nanoparticles have antimicrobial properties. This study aimed to investigate the effect of adding zirconia particles and nanoparticles, to denture adhesive on candidiasis.METHODSA total of 46 wells in 6 columns and 6 rows were selected from a cell culture plate. Equal amounts of Candida albicans and denture adhesive were added to all wells. Zirconia was then added to the first three rows at different concentrations of particles and the second three rows received different concentrations of nanoparticles, so that the concentrations were half the previous column. After 24 hours, by adding one type of Thiazolyl Blue Tetrazolium Bromide (MTT) to all the wells, the growth or lack of growth of C. albicans was investigated. Finally, the death or survival (merely lack of growth) of C. albicans was studied by sampling the wells with no growth.RESULTSC. albicans growth was seen in all concentrations of zirconia particles. However, it did not grow in all three rows of nanoparticles up to 31 µgr/mL concentration. Further, all wells with no growth continued to grow after removal of nanoparticles from the medium. Zirconium particles may have anti-candida properties at concentrations above 250 µgr/mL. However, nanoparticles with a minimum concentration of 31 µgr/mL inhibit the growth of C. albicans but do not cause death of these microorganisms.

The biological safety and biocompatibility evaluation of the mixture of Paris polyphylla-chitosan for denture adhesive / 实用口腔医学杂志

Objective:To study the biological safety and biocompatibility of the mixture of Paris polyphylla-chitosan.Methods:According to the GB/T 16886.12-2005 standard,YY/T 0279-1995 standard and GBT16886.5-2003 standard,samples were prepared and tested by oral mucous membrane irritation test,cytotoxicity test and flow cytometry.Results:No local response to the mixture of Paris polyphylla-chitosan was found,and the visual observation and pathological findings of oral mucosa were normal and similar to that of the control group.Therefore,the mixture of Paris polyphylla-chitosan had no irritation response to oral mucosa.The mixture of Paris polyphylla-chitosan showed no cytotoxicity to L929 cells,and did not affect the cycle distribution and apoptosis of L929 cells.Conclusion:The mixture of Paris polyphylla-chitosan has good bio-safety and biocompatibility.

Application of denture adhesive in the oral care / 口腔疾病防治

@#In recent years, the number of edentulous patients has been increasing with the increase of aging popula-tion and the number of patients with complete denture. Denture adhesive is an indispensable material of denture reten-tion intensifier in the clinic, which has been used for long periods in patients with full denture or partial denture. In this paper, we made a brief introduction according to the denture adhensive classification, mechanism of action, clinical at-tention and the latest research progress.

Denture adhesive Protefix relieves the discomfort of patients with complete denture / 实用口腔医学杂志

Denture adhesive(DA)Protefix was used in 31 edentulous patients with complete denture.NRS evaluation showed that applica-tion of Protefix decreased the uncomfortable score(P <0.05)at 2 h,1 d,7 d after use.Protefix improved denture retention,stability and masticatory function.

Prosthetic treatment for patient with upper lip cancer and severe periodontitis: Maxillary complete denture with denture adhesive and mandibular double crown-retained removable partial denture / 대한치과보철학회지

When oral cancer is occured, one may experience problems such as lip defect, necrosis of periodontal tissue and cervical caries caused by radiotherapy. According to ADI (Association of dental implantology), recent radiotherapy on jaw bone could be a relative contraindication of implant treatment. Due to this controversy, in most cases, treatment is done with removable dentures rather than implants. Especially, lip defect caused by an oral cancer operation have a serious repercussion on the retention of the denture. In this case report, patient with upper lip cancer had undergone resection primarily and secondary radiotherapy was done periodically. As a result, upper teeth of patient were extracted gradually and lower teeth showed very poor periodontal status. Therefore, Polident(R) denture adhesive cream (GlaxoSmithKline, London, England) was applied on maxillary complete denture to overcome reduced retention due to the lip defect and double crown RPD with friction pin was applied on the mandible successfully for two years.

An investigation into the effect of denture adhesives on incisal bite force of complete denture wearers using pressure transducers: a clinical study

PURPOSE: Study was conducted to determine and assess the effect of different type of denture adhesives on the incisal bite force of complete denture wearers until the dislodgement of upper denture, using pressure transducer. MATERIALS AND METHODS: 30 patients out of 100 were included in the study. Based on the Kapur's method of scoring denture retention and stability, these patients were divided into 3 groups- Group A - Clinically good dentures; Group B - Clinically fair dentures; and Group C - Clinically poor dentures. A custom made occlusal force meter was constructed based on the load cell type of pressure transducers. Different adhesives (powder, paste and adhesive strips) were used in the study. Complete denture wearers were asked to bite on the load cell and the readings of incisal bite force were recorded. The readings of incisal bite force were subjected to statistical analysis using Repeated measures ANOVA followed by post-hoc bonferroni test. RESULTS: The result suggests that denture adhesives improved the incisal bite force of complete denture wearers significantly The incisal bite force (in kg) in Group A without using adhesives, with powder adhesive, with paste adhesive and with adhesive strips was found to be 2.48 (+/- 0.16), 3.43 (+/- 0.11), 6.01 (+/- 0.11), 3.22 (+/- 0.09) respectively. The incisal bite force (in kg) in Group B without using adhesives, with powder adhesive, with paste adhesive and with adhesive strips was found to be 1.87 (+/- 0.18), 3.35 (+/- 0.14), 5.34 (+/- 0.18), 3.21 (+/- 0.12) respectively. The incisal bite force (in kg) in Group C without using adhesives, with powder adhesive, with paste adhesive and with adhesive strips was found to be 1.00 (+/- 0.17), 3.07 (+/- 0.14), 4.37 (+/- 0.26), 2.99 (+/- 0.14) respectively. CONCLUSION: Within the limitations of the study, it was concluded that the use of denture adhesive was found to be significantly effective in improving the incisal bite force of complete dentures until the dislodgement of upper denture. Fittydent paste adhesive was found to be more effective than the powder and strips adhesives. The improvement in incisal bite force was found to be higher in Group C in comparison to that of Group A and Group B.

In vitro evaluation of cytotoxicity of denture adhesives.

Aim: The aim of the study is to assess and compare the cytotoxicity of commercially available four denture adhesives ex-vivo. Materials and Methods: Four commercially available denture adhesives namely Metrodent powder, Fixon powder, Dentiro powder and Fixon cream were selected. Normal saline was used in control group. To evaluate the cytotoxicity of denture adhesives, macrophages were isolated from peritoneal cavity of Swiss albino mice and cell integrity/cell viability method was done by using trypan blue dye. Results: Viable cells were counted and subjected to statistical analysis. ANOVA, F and 't' test were performed, which showed statistically significant values (P < 0.001). The mean percentage of viable cells was highest in the control group (95%) and lowest in Fixon powder (55.66%), with Dentiro powder the mean percentage of viable cells was 63.66%, with Metrodent powder 67.6% while with Fixon cream it was 69.33%. Conclusion: All tested denture adhesives showed varied degree of cytotoxicity that is statistically significant. The degree of toxicity was more in Fixon powder followed by Dentiro powder and Metrodent powder with least in Fixon cream.

The knowledge and attitude of general dentists toward denture adhesives in Tehran.

Background: The purpose of this study was to generate discussion and communication among a group of general dentists in Tehran on their viewpoints regarding denture adhesives. Have they accepted denture adhesive as a material to enhance denture retention, stability and function? Materials and Methods: In the summer of 2007, a questionnaire was mailed to 300 general dentists who were assigned with a random systematic sampling method from general dentists in Tehran. The questions were arranged in two parts of evaluating knowledge and attitude. In evaluation of knowledge, dentists were classified into groups of good, moderate, weak and lack of knowledge. In evaluation of attitude, dentists were classified into positive, moderate and negative groups. (Evaluating attitude was carried out in good and moderate groups of knowledge.) Results: The study showed that 14%, 32% and 37% of the general dentists had respectively good, moderate and weak knowledge toward denture adhesive while 16.3% had no knowledge about this material. In evaluation of attitude through dentists with positive and moderate knowledge toward denture adhesive, 9.3%, 71.3% and 19.4% had respectively positive, moderate and negative attitude toward denture adhesive. The c2 test showed a significant statistical relation between situation of knowledge and experiences of dentists. Discussion: This study demonstrated that the rate of knowledge of these 300 general dentists in Tehran towards denture adhesives has not been in a good situation. It is believed that denture adhesive be able to enhance the fitness of a denture and provide psychological relief to the patient. Dentists agreed that education, not only for practitioners but also for patients, would raise the advantageous features and reduce the misuse of denture adhesive. Education of the topic "Denture adhesive" should be more concerned in dental universities.

Evaluation of changes in adhesive strength and cytotoxicity of a denture adhesive according to time / 대한치과보철학회지

STATEMENTS OF THE PROBLEM: Many denture wearers occasionally use denture adhesives to improve denture retention, stability and chewing efficiency. An ideal denture adhesive is nontoxic, non-irritating, and provides comfort to the oral mucosa. PURPOSE: The purpose of this study was to evaluate the cytotoxicity and adhesive properties of a selected denture adhesive. MATERIAL AND METHODS: To test cytotoxicity of the selected denture adhesive, mouse fibroblast cells were used in MTT testing. Cytotoxicity was examined according to the concentration of the denture adhesive and incubated for 1 to 4 days. To examine adhesive property, a denture base was fabricated on an edentulous dentiform. The adhesive was applied to the denture base, then tensile bond strength was measured, to evaluate the change in retention during 3 days. RESULTS AND CONCLUSION: 1. 1% and 2% concentration denture adhesive cream had no cytotoxicity. 2. The tensile bond strength of the group with both denture adhesive and artificial saliva was significantly higher than that of the group with only denture adhesive (P < .05). The tensile bond strength of the group with denture adhesive was significantly higher than that of with only artificial saliva (P < .05). 3. The tensile bond strength had no significant change during 1 hour, and then gradually decreased. After 1 day, it decrease to half. Within the limitation of this study, the tested denture adhesive had no cytotoxicilty and was effective in improving denture retention. The adhesive strength began to continuously decrease after 1 hour and it decreased to half at 1 day after application.